Description

1,4-Dichloro-6,7-Dimethoxyphthalazine is a versatile halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the construction of phthalazine-based drug candidates, including potential kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators with specific modes of action.
• Material Science Research: Used in the synthesis of organic ligands for metal-organic frameworks (MOFs) or as a monomer for specialty polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes.
• Dye & Pigment Intermediate: Acts as a precursor in the synthesis of complex heterocyclic dyes and functional pigments.
• Cross-Coupling Reactions: The chloro substituents make it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).

Basic Information

Product Name	1,4-Dichloro-6,7-Dimethoxyphthalazine
CAS No.	99161-51-0
Molecular Formula	C₁₀H₈Cl₂N₂O₂
Molecular Weight	259.09 g/mol
Synonyms	6,7-Dimethoxy-1,4-dichlorophthalazine; 1,4-Dichloro-6,7-dimethoxyphthalazine; 1,4-Dichloro-6,7-bis(methoxy)phthalazine; Phthalazine, 1,4-dichloro-6,7-dimethoxy-; NSC 405124; 99161-51-0; Dichlorodimethoxypothalamic
EINECS	Contact for details

Quality Control

Our 1,4-Dichloro-6,7-Dimethoxyphthalazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.