Description

(3S,αr)-3-[[(R)-4-[(R)-3-Amino-3-Carboxypropoxy]PhenylAcetyl]Amino]-α-[4-[(β-D-Glucopyranuronosyl)Oxy]Phenyl]-2-Oxo-1-Azetidineacetic Acid is a complex, high-purity azetidinone derivative with significant biochemical relevance. This compound serves as a critical advanced intermediate in the synthesis of novel therapeutic agents, particularly in the development of targeted enzyme inhibitors. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in producing next-generation antibiotics and specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel β-lactamase inhibitors and other specialized antibiotic candidates.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies targeting bacterial cell wall synthesis pathways.
• Medicinal Chemistry: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Process Development: Employed in the scale-up and optimization of synthetic routes for complex active pharmaceutical ingredients (APIs).
• High-Purity Fine Chemical: Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.

Basic Information

Product Name	(3S,αr)-3-[[(R)-4-[(R)-3-Amino-3-Carboxypropoxy]PhenylAcetyl]Amino]-α-[4-[(β-D-Glucopyranuronosyl)Oxy]Phenyl]-2-Oxo-1-Azetidineacetic Acid
CAS No.	99150-61-5
Molecular Formula	C31H36N4O14
Molecular Weight	688.64 g/mol
Synonyms	1-Azetidineacetic acid, 3-[[(R)-4-[(R)-3-amino-3-carboxypropoxy]phenylacetyl]amino]-α-[4-[(β-D-glucopyranuronosyl)oxy]phenyl]-2-oxo-, (3S,αR)-; (3S,αR)-3-[[(R)-4-[(R)-3-Amino-3-carboxypropoxy]phenylacetyl]amino]-α-[4-[(β-D-glucopyranuronosyl)oxy]phenyl]-2-oxo-1-azetidineacetic acid; Advanced β-lactam intermediate; Azetidinone-glucuronide conjugate; CAS 99150-61-5
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural integrity and purity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all critical quality attributes. We support development and commercial projects requiring material that meets ICH guidelines for impurities and stability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.