Description

n-(3-Fluoropropyl)-n-Normetazocine CAS NO 99134-12-0 is a specialized synthetic organic compound belonging to the benzomorphan class, characterized by its fluoropropyl substitution. This structural modification is of significant interest in advanced pharmaceutical research and development, particularly for studying receptor interactions and metabolic pathways. It serves as a critical intermediate or reference standard for researchers and manufacturers in the life sciences sector, enabling the development of novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel benzomorphan-derived compounds for pharmacological evaluation.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related substances.
• Medicinal Chemistry Research: A vital tool for structure-activity relationship (SAR) studies to explore the impact of fluorinated alkyl chains on bioactivity and selectivity.
• Neuropharmacology Studies: Employed in preclinical research to investigate interactions with central nervous system receptors.
• Metabolite Synthesis: Used for the preparation of potential metabolite standards for pharmacokinetic and metabolic stability studies.
• Process Chemistry Development: Acts as a model compound for optimizing synthetic routes and scaling up production of fluorinated pharmaceuticals.

Basic Information

Product Name	n-(3-Fluoropropyl)-n-Normetazocine
CAS No.	99134-12-0
Molecular Formula	C19H28FNO
Molecular Weight	305.43 g/mol
Synonyms	N-(3-Fluoropropyl)normetazocine; 1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(3-fluoropropyl)-2,6-methano-3-benzazocin-8-ol; 2'-(3-Fluoropropyl)-5,9-dimethyl-2'-hydroxy-6,7-benzomorphan; 3-(3-Fluoropropyl)-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol; (±)-N-(3-Fluoropropyl)normetazocine; 2'-Hydroxy-5,9-dimethyl-2'-(3-fluoropropyl)-6,7-benzomorphan
EINECS	Contact for details

Quality Control

Our n-(3-Fluoropropyl)-n-Normetazocine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This compound is sensitive to light and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.