Description

7-Bromo-2,3-Dihydrobenzo[B][1,4]Dioxine-6-Carbaldehyde is a high-value, multi-functional aromatic aldehyde building block characterized by its fused benzodioxine ring system and reactive bromo and formyl substituents. This compound matters for its versatility as a key synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets, leveraging its benzodioxine scaffold.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the bromine and aldehyde groups allow for further functionalization.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of organic electronic materials, such as novel polymers and small molecules for OLEDs or conductive films.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes due to its derivatizable functional groups.
• Custom Synthesis and Contract Manufacturing: A key building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical market.

Basic Information

Product Name	7-Bromo-2,3-Dihydrobenzo[B][1,4]Dioxine-6-Carbaldehyde
CAS No.	99067-25-1
Molecular Formula	C9H7BrO3
Molecular Weight	243.06 g/mol
Synonyms	7-Bromo-2,3-dihydro-1,4-benzodioxine-6-carboxaldehyde; 6-Bromo-2,3-dihydro-1,4-benzodioxine-7-carbaldehyde; 7-Bromo-2,3-dihydro-1,4-benzodioxin-6-carbaldehyde; 99067-25-1; 7-Bromo-2,3-dihydrobenzo-1,4-dioxine-6-carbaldehyde; 6-Formyl-7-bromo-2,3-dihydro-1,4-benzodioxine
EINECS	Contact for details

Quality Control

Our 7-Bromo-2,3-Dihydrobenzo[B][1,4]Dioxine-6-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.