Description

D-Cyclohexylalanine Hydrochloride is a high-purity, non-natural amino acid derivative essential for advanced pharmaceutical research and development. This chiral building block is critical for the synthesis of complex peptides and active pharmaceutical ingredients (APIs) with specific stereochemical requirements. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel therapeutic peptides and protease inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide chemistry to incorporate the D-cyclohexylalanine residue, which can enhance metabolic stability and binding affinity.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and structure-activity relationship (SAR) investigations.
• API Development: Employed in the research and scale-up production of Active Pharmaceutical Ingredients (APIs) requiring specific, non-proteinogenic amino acid motifs.
• Asymmetric Synthesis: Acts as a valuable precursor or auxiliary in catalytic asymmetric synthesis for creating enantiomerically pure compounds.

Basic Information

Item	Details
Product Name	D-Cyclohexylalanine Hydrochloride
CAS No.	99065-30-2
Molecular Formula	C9H17NO2 · HCl
Molecular Weight	207.70 g/mol
Synonyms	(R)-2-Amino-3-cyclohexylpropanoic acid hydrochloride; D-2-Amino-3-cyclohexylpropionic acid HCl; (R)-2-Amino-3-cyclohexylpropionic acid hydrochloride; D-3-Cyclohexylalanine hydrochloride; H-D-Cha-OH · HCl; D-α-Amino-β-cyclohexylpropionic acid hydrochloride; (R)-3-Cyclohexylalanine hydrochloride
EINECS	Contact for details

Quality Control

Our D-Cyclohexylalanine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.