Description

3-Phenyl-1,5-Epinitrilo-6,9-Methano-5A,6,9,9A-Tetrahydro-1,5-Dithia(Iv)-5H-2,4-Benzodiazepine CAS NO 99016-48-5 is a complex, high-purity heterocyclic compound featuring a unique benzodiazepine core fused with a dithia and methano bridge structure. This compound matters as a sophisticated chemical intermediate and research chemical for advanced synthetic programs, offering a rigid, multi-functional scaffold. It is primarily needed by pharmaceutical R&D teams and academic research institutions engaged in developing novel active pharmaceutical ingredients (APIs) and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel benzodiazepine-derived therapeutic agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Chemical Biology Probe: Utilized in the development of molecular probes to study biological pathways and protein interactions.
• Advanced Organic Synthesis: Acts as a challenging substrate for methodological development in heterocyclic and organosulfur chemistry.
• Academic & Institutional Research: Employed in university and government labs for fundamental research in chemical synthesis and molecular design.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	3-Phenyl-1,5-Epinitrilo-6,9-Methano-5A,6,9,9A-Tetrahydro-1,5-Dithia(Iv)-5H-2,4-Benzodiazepine
CAS No.	99016-48-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	3-Phenyl-1,5-epinitrilo-6,9-methano-5a,6,9,9a-tetrahydro-1,5-dithia(iv)-5H-2,4-benzodiazepine; 99016-48-5; 1,5-Dithia(iv)-5H-2,4-benzodiazepine, 3-phenyl-1,5-epinitrilo-6,9-methano-5a,6,9,9a-tetrahydro-; Benzodiazepine, 3-phenyl-1,5-epinitrilo-6,9-methano-5a,6,9,9a-tetrahydro-1,5-dithia(iv)-5H-2,4-; SCHEMBL21842227; DTXSID60672939
EINECS	Contact for details

Quality Control

Our 3-Phenyl-1,5-Epinitrilo-6,9-Methano-5A,6,9,9A-Tetrahydro-1,5-Dithia(Iv)-5H-2,4-Benzodiazepine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound may be light-sensitive and/or moisture-sensitive; handle and store under an inert atmosphere if specified for your grade. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.