Description

9-(2-Deoxy-2-Fluoro-β-D-Arabinofuranosyl)-1,9-Dihydro-6H-Purin-6-One is a high-purity nucleoside analog, a critical building block in advanced pharmaceutical research and development. Its primary value lies in its role as a key intermediate for the synthesis of antiviral and anticancer agents, particularly within the nucleoside drug class. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality raw materials for active pharmaceutical ingredient (API) synthesis and process development.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the development and production of novel antiviral agents targeting specific viral polymerases.
• Oncology Research: Serves as a building block for investigational chemotherapeutic compounds that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Employed in enzymatic studies and as a substrate or inhibitor in biochemical assays related to nucleotide metabolism.
• Process Chemistry & Scale-Up: Used in route scouting, optimization, and commercial-scale manufacturing of complex active pharmaceutical ingredients (APIs).
• Reference Standard: Functions as a high-purity analytical standard for quality control and regulatory submissions in drug development.

Basic Information

Product Name	9-(2-Deoxy-2-Fluoro-β-D-Arabinofuranosyl)-1,9-Dihydro-6H-Purin-6-One
CAS No.	98983-40-5
Molecular Formula	C10H12FN5O4
Molecular Weight	285.23 g/mol
Synonyms	2'-Fluoro-2'-deoxy-β-D-arabinofuranosyladenine; 2'-F-ara-A; 2'-Fluoro-arabinofuranosyladenine; 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)adenine; 2'-Fluoro-9-β-D-arabinofuranosyladenine; F-ara-A; 2'-F-Arabinofuranosyladenine; β-2'-Fluoro-2'-deoxyarabinofuranosyladenine
EINECS	Contact for details

Quality Control

Our 9-(2-Deoxy-2-Fluoro-β-D-Arabinofuranosyl)-1,9-Dihydro-6H-Purin-6-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities to meet the exacting standards required for pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH limits
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.