Description

2,3,4,5-Tetradehydro Alfuzosin Hydrochloride is a key pharmaceutical intermediate and reference standard used in the development and quality control of active pharmaceutical ingredients (APIs). This compound is critical for ensuring the purity, potency, and regulatory compliance of finished drug products. It is primarily utilized by research institutions, analytical laboratories, and manufacturers within the global pharmaceutical and life sciences sectors.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of Alfuzosin Hydrochloride and related therapeutic compounds.
• Analytical Reference Standard: Used for method development, validation, and quality control testing in HPLC, LC-MS, and other analytical techniques.
• Pharmacological Research: Employed in preclinical studies to investigate the properties and metabolism of α-1 adrenergic receptor antagonists.
• Impurity Profiling: Serves as a specified impurity standard to monitor and control the quality of Alfuzosin Hydrochloride API batches.
• Regulatory Compliance: Essential for generating data to meet the requirements of regulatory filings with agencies like the FDA and EMA.

Basic Information

Product Name	2,3,4,5-Tetradehydro Alfuzosin Hydrochloride
CAS No.	98902-29-5
Molecular Formula	C₁₉H₂₇N₅O₄ • HCl
Molecular Weight	425.91 g/mol
Synonyms	Alfuzosin Impurity F; Alfuzosin Related Compound F; N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide Hydrochloride; Alfuzosin EP Impurity F; Alfuzosin Hydrochloride Impurity F; 2,3,4,5-Tetrahydro-2-furancarboxamide, N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]-, monohydrochloride
EINECS	Contact for details

Quality Control

Our 2,3,4,5-Tetradehydro Alfuzosin Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent standards required for pharmaceutical reference materials. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.