Description

[17R,13α,(-)]-7α,17-Dihydroxy-2α,11α-Dimethoxy-8-Methyl-4-Methylene-1-Oxo-24-Nor-16,17-Seco-5α-Chola-14,20(22)-Diene-16,23-Dioic Acid 16,7:23,17-Dilactone is a complex, high-purity steroidal dilactone compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical advanced intermediate or reference standard for the synthesis and study of novel therapeutic agents, particularly in the fields of endocrinology and oncology. It is essential for R&D laboratories, process chemists, and analytical scientists requiring structurally defined, high-quality building blocks for drug discovery programs and method validation.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel steroid-based drug candidates targeting hormone receptors.
• Reference Standard: Used in analytical method development and validation (HPLC, LC-MS) for quality control and regulatory filings.
• Biochemical Research: Employed in studies investigating steroid biosynthesis pathways, enzyme inhibition, and receptor-ligand interactions.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for exploring new chemical entities and their biological activities.
• Custom Synthesis: A precursor for the preparation of specialized derivatives and analogs for proprietary drug discovery projects.

Basic Information

Item	Detail
Product Name	[17R,13α,(-)]-7α,17-Dihydroxy-2α,11α-Dimethoxy-8-Methyl-4-Methylene-1-Oxo-24-Nor-16,17-Seco-5α-Chola-14,20(22)-Diene-16,23-Dioic Acid 16,7:23,17-Dilactone
CAS No.	98874-66-9
Molecular Formula	C27H34O8
Molecular Weight	486.56 g/mol
Synonyms	24-Nor-16,17-seco-5α-chola-14,20(22)-diene-16,23-dioic acid, 7α,17-dihydroxy-2α,11α-dimethoxy-8-methyl-4-methylene-1-oxo-, 16,7:23,17-dilactone, (17R,13α)-; 16,17-Secochola-14,20(22)-diene dilactone derivative; 7α,17-Dihydroxy-2α,11α-dimethoxy-8-methyl-4-methylene-1-oxo-24-nor-16,17-seco-5α-chola-14,20(22)-diene-16,23-dioic acid dilactone; Steroidal dilactone intermediate; 98874-66-9; (17R,13α)-7α,17-Dihydroxy-2α,11α-dimethoxy-8-methyl-4-methylene-1-oxo-24-nor-16,17-seco-5α-chola-14,20(22)-diene-16,23-dioic acid 16,7:23,17-dilactone
EINECS	Contact for details

Quality Control

Our [17R,13α,(-)]-7α,17-Dihydroxy-2α,11α-Dimethoxy-8-Methyl-4-Methylene-1-Oxo-24-Nor-16,17-Seco-5α-Chola-14,20(22)-Diene-16,23-Dioic Acid 16,7:23,17-Dilactone is manufactured under strict quality control protocols suitable for research and development applications. Each batch is analyzed using advanced techniques including HPLC, NMR, and MS to ensure structural identity and high purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical data is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.