Description

9-[(1R,2S,3R,4S)-2,3-Dihydroxy-4-Methylcyclopentyl]-1,6-Dihydro-9H-Purin-6-One is a high-purity, stereochemically defined nucleoside analogue of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel antiviral and anticancer agents, where its specific stereochemistry is essential for biological activity. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of nucleoside-based antiviral drugs.
• Antiviral Agent Research: Investigated as a precursor for potential therapeutics targeting viral polymerases.
• Oncology Research: Used in the development of purine analogues with potential anticancer properties.
• Biochemical Tool: Employed in enzymatic studies to understand nucleoside metabolism and inhibition.
• Process Chemistry: Serves as a starting material for scale-up and optimization of active pharmaceutical ingredient (API) manufacturing processes.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	9-[(1R,2S,3R,4S)-2,3-Dihydroxy-4-Methylcyclopentyl]-1,6-Dihydro-9H-Purin-6-One
CAS No.	98873-79-1
Molecular Formula	C12H16N4O4
Molecular Weight	280.28 g/mol
Synonyms	(1R,2S,3R,4S)-4-Methyl-2,3-dihydroxycyclopentyl Purine-6-one; 9-[(1R,2S,3R,4S)-2,3-Dihydroxy-4-methylcyclopentyl]purin-6(1H)-one; Carbocyclic nucleoside analogue; c-DHPA derivative; (1'R,2'S,3'R,4'S)-9-(2',3'-Dihydroxy-4'-methylcyclopentyl)hypoxanthine
EINECS	Contact for details

Quality Control

Our 9-[(1R,2S,3R,4S)-2,3-Dihydroxy-4-Methylcyclopentyl]-1,6-Dihydro-9H-Purin-6-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and residual solvent analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.