Description

3'-Azido-3'-Deoxyguanosine CAS NO 98870-11-2 is a modified nucleoside analog, a crucial building block in nucleic acid chemistry and medicinal research. Its unique azido-functionalized structure makes it an invaluable intermediate for synthesizing nucleotide prodrugs and for applications in bioorthogonal chemistry, such as click reactions. This high-purity compound is essential for researchers and manufacturers in pharmaceutical development, particularly for antiviral and anticancer drug discovery, as well as in academic research focused on oligonucleotide synthesis and labeling.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analog prodrugs for antiviral and anticancer therapies.
• Bioorthogonal Chemistry: Utilized in Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) "click" reactions for bioconjugation and labeling of biomolecules.
• Oligonucleotide Synthesis: Serves as a modified building block for introducing functional handles into DNA or RNA strands.
• Proteomics & Genomics Research: Used in the development of probes and tools for studying nucleic acid-protein interactions and cellular processes.
• Chemical Biology Tool Development: Integral for creating activity-based probes and diagnostic agents.
• Antiviral Research: Investigated as a potential scaffold for the development of novel antiviral agents targeting viral polymerases.

Basic Information

Product Name	3'-Azido-3'-Deoxyguanosine
CAS No.	98870-11-2
Molecular Formula	C10H12N8O4
Molecular Weight	308.26 g/mol
Synonyms	3'-Azido-2',3'-dideoxyguanosine; 3'-N3-dG; 9-[(2R,5S)-5-Azido-5-deoxy-β-D-ribofuranosyl]guanine; 3'-Azido-3'-deoxyguanosine; 3'-Azido-ddG; Azidodeoxyguanosine; Guanosine, 3'-azido-3'-deoxy-; 98870-11-2
EINECS	Contact for details

Quality Control

Our 3'-Azido-3'-Deoxyguanosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.