Description

(2R,3R)-3-(n-Boc-Amino)-1-Oxirane-4-Phenylbutane is a high-purity chiral epoxide building block, CAS number 98818-34-9, designed for advanced synthetic chemistry. This compound is a critical intermediate for the stereoselective synthesis of complex pharmaceutical molecules, offering precise control over three-dimensional molecular architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, renin inhibitors, and other biologically active compounds.
• Asymmetric Synthesis: Used in the construction of complex natural products and novel chemical entities where stereochemical integrity is paramount.
• Peptidomimetics Research: Serves as a constrained scaffold for developing peptide analogs with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Employed in the creation of labeled or tagged molecules for studying enzyme mechanisms and protein-ligand interactions.
• Process Chemistry Development: Used in route scouting and optimization for the scalable production of chiral drug candidates.
• Academic Research: A valuable reagent for methodological studies in organic synthesis and catalysis.

Basic Information

Item	Detail
Product Name	(2R,3R)-3-(n-Boc-Amino)-1-Oxirane-4-Phenylbutane
CAS No.	98818-34-9
Molecular Formula	C₁₇H₂₅NO₄
Molecular Weight	307.39 g/mol
Synonyms	(2R,3R)-1,2-Epoxy-3-[(tert-butoxycarbonyl)amino]-4-phenylbutane; (2R,3R)-3-[(tert-Butoxycarbonyl)amino]-1,2-epoxy-4-phenylbutane; (2R,3R)-3-(Boc-Amino)-1,2-epoxy-4-phenylbutane; (2R,3R)-N-Boc-3-amino-1,2-epoxy-4-phenylbutane; (2R,3R)-3-Amino-1,2-epoxy-4-phenylbutane N-Boc derivative; BOC-(2R,3R)-Aminoepoxyphenylbutane; tert-Butyl (2R,3R)-2,3-epoxy-1-phenyl-4-butylcarbamate
EINECS	Contact for details

Quality Control

Our (2R,3R)-3-(n-Boc-Amino)-1-Oxirane-4-Phenylbutane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.