Description

5,10-Diformyl-5,6,7,8-Tetrahydro Folic Acid is a key derivative in the folate pathway, serving as a critical intermediate in the synthesis of biologically active coenzymes. Its precise chemical structure makes it an essential building block for advanced pharmaceutical research and development. This high-purity intermediate is primarily sought by manufacturers in the pharmaceutical and fine chemical sectors for the production of active pharmaceutical ingredients (APIs) and specialized biochemical reagents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antifolate drugs and targeted cancer therapeutics.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies related to folate metabolism and one-carbon transfer reactions.
• Nutraceutical Development: Serves as an advanced intermediate for the development of next-generation, high-bioavailability folate supplements.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex molecules requiring a functionalized tetrahydrofolate core structure.
• Diagnostic Reagent Manufacturing: Utilized in the production of components for clinical diagnostic kits that measure folate levels or related enzymatic activity.

Basic Information

Product Name	5,10-Diformyl-5,6,7,8-Tetrahydro Folic Acid
CAS No.	98814-60-9
Molecular Formula	C20H23N7O7
Molecular Weight	473.44 g/mol
Synonyms	5,10-Diformyltetrahydrofolic Acid; 5,10-Diformyl-THF; 5,10-Diformyl-5,6,7,8-tetrahydrofolate; 5,10-CHO-THF; 5,10-Diformyl-H4 folate; 5,10-Diformyltetrahydropteroylglutamic Acid; NSC 154032; 5,10-Diformyl-5,6,7,8-tetrahydroperoyl-L-glutamic Acid
EINECS	Contact for details

Quality Control

Our 5,10-Diformyl-5,6,7,8-Tetrahydro Folic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use and inert atmosphere packing.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Solubility	Soluble in alkaline aqueous solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.