Description

(2Rs,3Rs)-3-(2-Ethoxyphenoxy)-2-Hydroxy-1-(4-Nitrobenzoyloxy)-3-Phenylpropane is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its precise chiral structure makes it a valuable building block for the development of complex, biologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical development teams working on novel therapeutic agents and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or cardiovascular targets.
• Asymmetric Synthesis: Utilized as a sophisticated building block in stereoselective synthesis to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a core scaffold or a derivatization point for structure-activity relationship (SAR) studies in drug discovery programs.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value organic compounds requiring specific stereochemistry.
• Academic & Industrial R&D: Used in chemical research laboratories for methodological development and the study of reaction mechanisms involving chiral centers and ether linkages.

Basic Information

Product Name	(2Rs,3Rs)-3-(2-Ethoxyphenoxy)-2-Hydroxy-1-(4-Nitrobenzoyloxy)-3-Phenylpropane
CAS No.	98769-70-1
Molecular Formula	C24H23NO7
Molecular Weight	437.44 g/mol
Synonyms	1-(4-Nitrobenzoyloxy)-3-(2-ethoxyphenoxy)-2-hydroxy-3-phenylpropane (2R,3R)-Isomer; (2R,3R)-3-(2-Ethoxyphenoxy)-2-hydroxy-1-[(4-nitrophenyl)carbonyl]oxy]-3-phenylpropane; 3-(2-Ethoxyphenoxy)-2-hydroxy-1-(4-nitrobenzoyloxy)-3-phenylpropane, (2R,3R)-; Propane, 3-(2-ethoxyphenoxy)-2-hydroxy-1-[(4-nitrophenyl)carbonyl]oxy]-3-phenyl-, (2R,3R)-; (2R,3R)-rel-3-(2-Ethoxyphenoxy)-2-hydroxy-1-[(4-nitrophenyl)carbonyl]oxy]-3-phenylpropane
EINECS	Contact for details

Quality Control

Our (2Rs,3Rs)-3-(2-Ethoxyphenoxy)-2-Hydroxy-1-(4-Nitrobenzoyloxy)-3-Phenylpropane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We support customer-specific analytical requirements and can provide material compliant with cGMP standards for advanced pharmaceutical development stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.