Description

Avermectinb1A8,9-Epoxide is a key chemical intermediate derived from the avermectin family, known for its potent biological activity. This compound is crucial for the synthesis of advanced agrochemicals and pharmaceutical agents, offering a high-purity building block for complex molecular transformations. It is primarily sought by research institutions and manufacturers in the agrochemical and pharmaceutical industries for developing next-generation crop protection solutions and active pharmaceutical ingredients.

Application

• Agrochemical Intermediate: A critical precursor in the synthesis of novel, high-efficacy insecticides and acaricides.
• Pharmaceutical Research: Used as a building block for developing antiparasitic and anthelmintic drug candidates.
• Veterinary Medicine: Employed in the research and development of formulations for animal health products.
• Biochemical Studies: Serves as a reference standard or active component in mode-of-action and resistance studies.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for specialized chemical entities.

Basic Information

Product Name	Avermectinb1A8,9-Epoxide
CAS No.	98734-60-2
Molecular Formula	C48H72O15
Molecular Weight	889.1 g/mol
Synonyms	(2aE,4E,8E)-(5'R,6S,6'S,7S,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(S)-sec-Butyl]-5',6,6',7,10,11,14,15,17a,20,20a,20b-dodecahydro-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxospiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-[2H]pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-3-O-methyl-α-L-arabino-hexopyranoside; Avermectin B1a 8,9-Epoxide; 8,9-Epoxy Avermectin B1a; Abamectin 8,9-Epoxide
EINECS	Contact for details

Quality Control

Our Avermectinb1A8,9-Epoxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.