Description

Z-Ser(Bzl)-Osu is a protected serine derivative, specifically the N-benzyloxycarbonyl (Z) protected serine benzyl ester activated with an N-hydroxysuccinimide (Osu) ester group. This compound is a crucial building block in peptide synthesis, offering high reactivity and selectivity for coupling reactions under mild conditions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for the production of peptides, peptidomimetics, and other bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key reagent for the efficient incorporation of serine residues into peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical peptide coupling methodologies to construct complex peptide sequences.
• Pharmaceutical Intermediate: Serves as a critical intermediate in the synthesis of therapeutic peptides and peptide-based drugs.
• Bioconjugation: Facilitates the site-specific labeling or modification of proteins, antibodies, and other biomolecules.
• Research & Development: Essential for academic and industrial R&D in medicinal chemistry and chemical biology for exploring new bioactive compounds.
• Production of Peptidomimetics: Used to create stable analogs of natural peptides with enhanced pharmacological properties.

Basic Information

Item	Details
Product Name	Z-Ser(Bzl)-Osu
CAS No.	98647-23-5
Molecular Formula	C19H18N2O7
Molecular Weight	386.36 g/mol
Synonyms	Nα-Benzyloxycarbonyl-O-benzyl-L-serine N-hydroxysuccinimide ester; Z-O-Benzyl-L-serine N-hydroxysuccinimide ester; Z-Ser(Bzl)-OSu; Cbz-Ser(Bzl)-OSu; N-Cbz-O-benzyl-L-serine succinimidyl ester; Benzyl N-[(benzyloxy)carbonyl]-L-seryl]carbamate, active ester; NSC 334381; (S)-2-(((Benzyloxy)carbonyl)amino)-3-(benzyloxy)propanoic acid 2,5-dioxopyrrolidin-1-yl ester
EINECS	Contact for details

Quality Control

Our Z-Ser(Bzl)-Osu is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric integrity, and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]D20	-10.0° to -15.0° (c=1 in DMF)
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.