Description

tert-Butyl n-{3-[(tert-Butoxycarbonyl)Amino]-2-Hydroxypropyl}Carbamate is a high-purity, protected amino alcohol derivative of significant value in advanced organic synthesis. This compound is specifically engineered to serve as a critical building block for the construction of complex molecules, offering orthogonal protection for amine and alcohol functionalities. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), peptide mimetics, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the preparation of modified amino acids and as a scaffold for constructing peptide mimetics with enhanced stability.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) groups provide orthogonal protection for amine functionalities during complex synthetic sequences.
• Ligand and Catalyst Synthesis: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal complex formation.
• Bioconjugation: Employed in the development of linkers and spacers for antibody-drug conjugates (ADCs) and other bioconjugation applications.
• Academic & Industrial Research: A valuable reagent for methodological development and the synthesis of complex natural product analogs in R&D settings.

Basic Information

Product Name	tert-Butyl n-{3-[(tert-Butoxycarbonyl)Amino]-2-Hydroxypropyl}Carbamate
CAS No.	98642-15-0
Molecular Formula	C13H26N2O5
Molecular Weight	290.36 g/mol
Synonyms	1,3-Bis-Boc-2-hydroxypropylamine; 3-[(tert-Butoxycarbonyl)amino]-2-hydroxypropyl tert-butylcarbamate; 2-Hydroxy-1,3-propanediamine, N1,N3-bis(1,1-dimethylethoxy)carbonyl]-; N,N'-Di-Boc-2-hydroxy-1,3-propanediamine; 1,3-Di-Boc-2-hydroxypropylamine; (2-Hydroxy-1,3-propanediyl)bis[carbamic acid] bis(1,1-dimethylethyl) ester; Bis-Boc protected aminodiol
EINECS	Contact for details

Quality Control

Our tert-Butyl n-{3-[(tert-Butoxycarbonyl)Amino]-2-Hydroxypropyl}Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and support your research and cGMP compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.