Description

De-(n-Methyl)-8,9-Anhydroerythromycin A 6,9-Hemicetal is a key chemical intermediate and derivative of the macrolide antibiotic erythromycin. This compound is of significant value in pharmaceutical research and development, particularly for the synthesis of novel antibiotic agents and the study of structure-activity relationships. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in advanced antibiotic development and process chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of next-generation macrolide antibiotics and semi-synthetic derivatives.
• Research & Development: Used in academic and industrial laboratories for pharmacological studies, metabolic pathway research, and mechanism of action investigations.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical manufacturing.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for complex active pharmaceutical ingredients (APIs).
• Biochemical Tool: Utilized in studies exploring bacterial ribosome binding and antibiotic resistance mechanisms.

Basic Information

Product Name	De-(n-Methyl)-8,9-Anhydroerythromycin A 6,9-Hemicetal
CAS No.	98641-05-5
Molecular Formula	C36H63NO12
Molecular Weight	701.89 g/mol
Synonyms	8,9-Anhydroerythromycin A 6,9-hemiketal; 8,9-Anhydro-N-demethylerythromycin A 6,9-hemiketal; N-Demethyl-8,9-anhydroerythromycin A 6,9-hemiketal; Erythromycin A, 8,9-anhydro-N-demethyl-, 6,9-hemiketal; 8,9-Anhydro-N-demethylerythromycin A; De-(N-methyl)-8,9-anhydroerythromycin A 6,9-hemiketal; 98641-05-5
EINECS	Contact for details

Quality Control

Our De-(n-Methyl)-8,9-Anhydroerythromycin A 6,9-Hemicetal is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.