Description

(+)-Methyl-Prop-2-Ynyl-(1,2,3,4-Tetrahydro-Naphthalen-2-Yl)-Amine Hydrochloride is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a defined stereochemical center and a protected amine functionality, enabling the efficient construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of central nervous system (CNS) active drugs, potential antidepressants, and neuroprotective agents.
• Agrochemical Synthesis: Used in the creation of novel, enantiomerically pure pesticides and herbicides where specific stereochemistry impacts biological activity.
• Chemical Biology & Proteomics: Acts as a versatile scaffold or linker in the design of molecular probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Asymmetric Catalysis Research: Employed as a precursor or ligand in the development of new chiral catalysts for stereoselective transformations.
• Academic & Institutional R&D: Fundamental research tool in synthetic organic chemistry for methodology development and total synthesis of natural products.
• Preclinical Candidate Development: Supports medicinal chemistry programs during lead optimization and the synthesis of candidate compounds for biological evaluation.

Basic Information

Product Name	(+)-Methyl-Prop-2-Ynyl-(1,2,3,4-Tetrahydro-Naphthalen-2-Yl)-Amine Hydrochloride
CAS No.	98640-74-5
Molecular Formula	C15H20ClN
Molecular Weight	249.78 g/mol
Synonyms	(+)-N-Methyl-N-(2-propynyl)-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride; (2S)-N-Methyl-N-(prop-2-yn-1-yl)-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride; (S)-N-Methyl-N-(prop-2-ynyl)-1,2,3,4-tetrahydronaphthalen-2-amine HCl; (2S)-1,2,3,4-Tetrahydro-N-methyl-N-(2-propynyl)-2-naphthalenamine hydrochloride; (S)-Methylpropynyltetralinamine hydrochloride; Ritalinic acid intermediate derivative; MPH derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of (+)-Methyl-Prop-2-Ynyl-(1,2,3,4-Tetrahydro-Naphthalen-2-Yl)-Amine Hydrochloride is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles verified by techniques such as HPLC, GC, and NMR. Our quality commitment ensures material consistency and traceability, supporting your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.