Description

(R)-Benzyl 2-Oxooxetan-3-Ylcarbamate is a high-value, chiral β-lactam derivative that serves as a critical synthetic intermediate in advanced pharmaceutical manufacturing. Its enantiopure structure is essential for constructing complex molecules with precise stereochemistry, directly impacting the efficacy and safety of final drug products. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel antibiotics, protease inhibitors, and other active pharmaceutical ingredients (APIs) where the (R)-configured oxetanone scaffold is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel β-lactam antibiotics and other therapeutic agents.
• Protease Inhibitor Development: Used in research and production of inhibitors targeting various serine proteases.
• Chiral Synthesis: Serves as a versatile, enantiopure starting material or intermediate in asymmetric synthesis for complex organic molecules.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore new bioactive compounds.
• API Manufacturing: Integrated into the commercial-scale production pathways for specific, high-value active pharmaceutical ingredients.
• Chemical Biology Probes: Utilized in the development of activity-based probes for studying enzyme function and mechanism.

Basic Information

Product Name	(R)-Benzyl 2-Oxooxetan-3-Ylcarbamate
CAS No.	98632-91-8
Molecular Formula	C11H11NO4
Molecular Weight	221.21 g/mol
Synonyms	(R)-3-[(Benzyloxycarbonyl)amino]-2-oxetanone; (R)-3-[(Cbz-Amino)-2-oxetanone; (3R)-3-{[(Benzyloxy)carbonyl]amino}oxetan-2-one; (R)-N-Cbz-3-Amino-2-oxetanone; Carbamic acid, N-[(3R)-2-oxo-3-oxetanyl]-, phenylmethyl ester; (R)-β-Lactam Cbz derivative; (R)-Cbz-3-Amino-2-oxetanone
EINECS	Contact for details

Quality Control

Our (R)-Benzyl 2-Oxooxetan-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.