Description

Boc-L-2-Amino-5-Phenyl-Pentanoic Acid CAS NO 98628-27-4 is a protected amino acid derivative, specifically a Boc-protected analog of L-homophenylalanine. This compound is a critical building block in the synthesis of complex peptides and peptidomimetics, offering a versatile chiral center for pharmaceutical research. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediates: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis (Solid-Phase & Solution-Phase): Used as a protected amino acid for the controlled assembly of peptides, particularly those requiring the homophenylalanine side chain.
• Protease Inhibitor Development: Acts as a core structural component in the design and synthesis of protease inhibitors due to its phenylalkyl side chain.
• Chemical Biology & Biochemical Research: Employed in the preparation of labeled peptides, enzyme substrates, and molecular probes for studying biological mechanisms.
• Combinatorial Chemistry Libraries: A valuable building block for generating diverse compound libraries for high-throughput screening.
• Agrochemical Research: Potential intermediate in the development of novel, biologically active compounds for crop protection.

Basic Information

Product Name	Boc-L-2-Amino-5-Phenyl-Pentanoic Acid
CAS No.	98628-27-4
Molecular Formula	C₁₆H₂₃NO₄
Molecular Weight	293.36 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-homophenylalanine; Boc-L-Homophe-OH; (2S)-2-[(tert-Butoxycarbonyl)amino]-5-phenylpentanoic acid; Boc-Hph-OH; N-Boc-L-2-amino-5-phenylvaleric acid; Boc-L-2-Amino-5-phenylvaleric acid; N-α-Boc-L-homophenylalanine; tert-Butyloxycarbonyl-L-homophenylalanine
EINECS	Contact for details

Quality Control

Our Boc-L-2-Amino-5-Phenyl-Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.