Description

Benzyl-Peg3-Tos CAS NO 98627-22-6 is a high-purity, functionalized polyethylene glycol (PEG) derivative featuring a benzyl group and a tosylate leaving group, connected by a triethylene glycol spacer. This compound is a critical building block in organic synthesis and bioconjugation, enabling the precise introduction of PEG chains to enhance the solubility, stability, and pharmacokinetic properties of target molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications ranging from drug discovery to polymer chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key reagent in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• PEGylation Reagent: Used to attach polyethylene glycol chains to peptides, proteins, and small molecule drugs to improve their half-life and reduce immunogenicity.
• Linker Chemistry: Acts as a versatile heterobifunctional linker in bioconjugation strategies, connecting different functional entities.
• Polymer Synthesis: Employed as a monomer or functional initiator in the preparation of specialized PEG-based copolymers and hydrogels.
• Surface Modification: Facilitates the functionalization of nanoparticles, biosensors, and other material surfaces to impart specific chemical properties.
• Chemical Biology Probes: Used in the development of probes and tools for studying biological processes and interactions.

Basic Information

Item	Detail
Product Name	Benzyl-Peg3-Tos
CAS No.	98627-22-6
Molecular Formula	C21H28O6S
Molecular Weight	408.51 g/mol
Synonyms	1-Benzyl-2,5,8,11-tetraoxatridecan-13-yl 4-methylbenzenesulfonate; Benzyl-triethylene glycol tosylate; Benzyl-PEG3-OTs; 2-[2-[2-(Benzyloxy)ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate; Tos-PEG3-OBn; Benzyl-PEG3-tosylate; Benzyl 15-tosyl-3,6,9,12-tetraoxapentadecyl ether; Bn-PEG3-OTs
EINECS	Contact for details

Quality Control

Our Benzyl-Peg3-Tos is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material is suitable for demanding applications in GMP-compatible synthesis and research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.