Description

n-Methyl-1H-Indole-5-Ethanesulphonamide is a specialized organic compound belonging to the indole sulphonamide class, serving as a key synthetic intermediate in advanced pharmaceutical research and development. Its value lies in its functionalized indole core, which is a privileged scaffold for designing bioactive molecules with targeted therapeutic effects. This high-purity building block is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries, particularly for the synthesis of novel drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores with improved efficacy and selectivity.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs) under cGMP conditions.
• Biochemical Tool Compound: Serves as a precursor or reference standard in the development of enzyme inhibitors or receptor modulators for biological assays.
• Agrochemical Research: Potential intermediate in the research and development of new crop protection agents and pesticides.

Basic Information

Product Name	n-Methyl-1H-Indole-5-Ethanesulphonamide
CAS No.	98623-50-8
Molecular Formula	C11H14N2O2S
Molecular Weight	238.31 g/mol
Synonyms	5-(2-Sulfamoylethyl)-1-methylindole; 1-Methyl-5-(2-sulfamoylethyl)indole; N-Methyl-5-(2-amino sulfonylethyl)indole; 5-(2-Sulfamoylethyl)-N-methylindole; 1-Methyl-1H-indole-5-ethanesulfonamide; 98623-50-8; Indole-5-ethanesulfonamide, 1-methyl-
EINECS	Contact for details

Quality Control

Our n-Methyl-1H-Indole-5-Ethanesulphonamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch to guarantee compliance with your specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.