Description

6-(2-Chlorophenyl)-4H-Imidazo[1,5-A][1,4]Benzodiazepine-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate belonging to the imidazobenzodiazepine class of compounds. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and for research into central nervous system (CNS) therapeutics. Pharmaceutical manufacturers, biotechnology R&D labs, and academic research institutions need this material for developing new drug candidates and conducting pharmacological studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel benzodiazepine-derived active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• CNS Drug Discovery: Employed in preclinical research for investigating compounds targeting GABAA receptors and related neurological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for pharmacological and biochemical studies.

Basic Information

Item	Details
Product Name	6-(2-Chlorophenyl)-4H-Imidazo[1,5-A][1,4]Benzodiazepine-3-Carboxamide
CAS No.	98601-60-6
Molecular Formula	C18H13ClN4O
Molecular Weight	336.77 g/mol
Synonyms	6-(2-Chlorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxamide; 98601-60-6; Imidazo[1,5-a][1,4]benzodiazepine-3-carboxamide, 6-(2-chlorophenyl)-4H-; 6-(2-Chlorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxamide; 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxamide, 6-(2-chlorophenyl)-
EINECS	Contact for details

Quality Control

Our 6-(2-Chlorophenyl)-4H-Imidazo[1,5-A][1,4]Benzodiazepine-3-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical R&D and intermediate use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.