Description

(S)-2-(Hydroxymethyl)-1,4-Benzodioxane is a chiral benzodioxane derivative of significant interest in fine chemical synthesis. This compound serves as a valuable chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate its specific stereochemistry into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Building block for creating chiral active ingredients in herbicides, fungicides, and insecticides, where stereochemistry can impact efficacy and environmental profile.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis, enabling more efficient and selective chemical transformations.
• Material Science Research: Intermediate for synthesizing chiral monomers or additives aimed at modifying polymer properties for optical or electronic applications.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process development for stereoselective synthesis routes.

Basic Information

Product Name	(S)-2-(Hydroxymethyl)-1,4-Benzodioxane
CAS No.	98572-00-0
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	(S)-1,4-Benzodioxan-2-ylmethanol; (S)-2-Hydroxymethyl-1,4-benzodioxane; (S)-2-(Hydroxymethyl)-1,4-benzodioxin; (S)-2-Methanol-1,4-benzodioxane; (2S)-2-(Hydroxymethyl)-1,4-benzodioxane; (S)-Benzodioxanylmethanol; (S)-1,4-Benzodioxane-2-methanol; (S)-BDO-OH
EINECS	Contact for details

Quality Control

Our (S)-2-(Hydroxymethyl)-1,4-Benzodioxane is produced under a strict quality management system. Each batch is fully characterized and tested to ensure identity, purity, and enantiomeric excess meet the required specifications for advanced synthetic applications. Certificates of Analysis (COA) detailing chiral purity (by chiral HPLC or GC), chemical purity, and specific rotation are provided. We support development and cGMP requirements for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.