Description

Proline, 3-Hydroxy-4-Isopropyl- (6Ci) is a specialized, non-proteinogenic proline derivative characterized by its unique hydroxyl and isopropyl substituents. This compound matters as a versatile chiral building block and intermediate for synthesizing complex molecules with potential biological activity. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for peptidomimetics and protease inhibitors.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, or plant growth regulators that incorporate modified amino acid structures.
• Fine Chemical Synthesis: Acts as a building block for creating complex, high-value specialty chemicals, flavors, and fragrances.
• Biochemical Research: Employed in studies of enzyme inhibition, metabolic pathways, and as a precursor for labeled compounds in tracer studies.
• Peptide Chemistry: Incorporated into custom peptides to study structure-activity relationships (SAR) or to confer specific conformational properties.
• Catalyst & Ligand Development: Potential use in the design of chiral catalysts or ligands for asymmetric synthesis.

Basic Information

Item	Details
Product Name	Proline, 3-Hydroxy-4-Isopropyl- (6Ci)
CAS No.	98553-04-9
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	3-Hydroxy-4-isopropylproline; 4-Isopropyl-3-hydroxyproline; (2S,3S,4S)-3-Hydroxy-4-(1-methylethyl)-L-proline; 3-Hydroxy-4-(1-methylethyl)-L-proline; 4-(1-Methylethyl)-3-hydroxy-L-proline; L-Proline, 3-hydroxy-4-(1-methylethyl)-; A non-proteinogenic proline derivative
EINECS	Contact for details

Quality Control

Our Proline, 3-Hydroxy-4-Isopropyl- (6Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting key parameters such as assay, chiral purity, and impurity profiles are available upon request. We support cGMP standards for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.