Description

1,4-Pregnadien-11-Beta, 17,21-Triol-3,20-Dione 11,21-Diacetate CAS NO 98523-85-4 is a high-purity steroid derivative, primarily utilized as a critical pharmaceutical intermediate. Its value lies in its role as a key building block for the synthesis of more complex corticosteroid APIs, ensuring process reliability and final product quality. This compound is essential for R&D laboratories and manufacturing facilities in the pharmaceutical and fine chemical sectors requiring consistent, high-grade raw materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent corticosteroid active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the development and optimization of new steroidal drug candidates.
• Process Chemistry: Serves as a standardized starting material or intermediate in multi-step GMP manufacturing processes.
• Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Used in studies investigating steroid hormone metabolism, receptor binding, and biological activity.

Basic Information

Product Name	1,4-Pregnadien-11-Beta, 17,21-Triol-3,20-Dione 11,21-Diacetate
CAS No.	98523-85-4
Molecular Formula	C₂₅H₃₂O₈
Molecular Weight	460.52 g/mol
Synonyms	11β,17,21-Trihydroxy-1,4-pregnadiene-3,20-dione 11,21-diacetate; Prednisolone 11,21-Diacetate; 1,4-Pregnadiene-11β,17α,21-triol-3,20-dione 11,21-diacetate; NSC 134455; 11β-Hydroxyprednisolone 11,21-diacetate; Prednisolone 21-acetate 11-acetate; 11β,21-Diacetoxypregna-1,4-diene-3,20-dione
EINECS	Contact for details

Quality Control

Our 1,4-Pregnadien-11-Beta, 17,21-Triol-3,20-Dione 11,21-Diacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical intermediate use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.