Description

cis-2-Benzylaminomethyl-1-Cyclooctanol Hydrochloride is a functionalized cyclooctanol derivative with a benzylaminomethyl substituent, supplied as its stable hydrochloride salt. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the development of complex molecules with potential biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to introduce specific stereochemistry and functional groups.
• Asymmetric Synthesis: Employed as a precursor or ligand in catalytic asymmetric reactions due to its rigid cyclooctane backbone and amine functionality.
• Chemical Biology Probes: Useful for the synthesis of molecular probes to study enzyme mechanisms or protein-ligand interactions.
• Fine Chemical Production: Serves as a specialized intermediate in the multi-step synthesis of high-value agrochemicals or performance chemicals.

Basic Information

Product Name	cis-2-Benzylaminomethyl-1-Cyclooctanol Hydrochloride
CAS No.	98516-20-2
Molecular Formula	C16H25NO•HCl
Molecular Weight	283.84 g/mol
Synonyms	1-Cyclooctanol, 2-[(phenylmethyl)amino]methyl]-, hydrochloride, (1R,2S)-rel-; cis-2-[(Benzylamino)methyl]cyclooctanol hydrochloride; 2-(Benzylaminomethyl)cyclooctanol hydrochloride; (1R,2S)-2-((Benzylamino)methyl)cyclooctan-1-ol hydrochloride; rel-(1R,2S)-2-((Benzylamino)methyl)cyclooctan-1-ol hydrochloride
EINECS	Contact for details

Quality Control

Our cis-2-Benzylaminomethyl-1-Cyclooctanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation via spectroscopic methods. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% de (cis-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.