Description

p-Nitrobenzyl-6,6-Dibromopenicillinate is a specialized, high-value chemical intermediate primarily used in advanced pharmaceutical synthesis. This compound is critical for researchers and manufacturers developing novel β-lactam antibiotics and other fine chemicals, offering a key building block with precise bromination and protective group functionality. It is essential for R&D laboratories, process development chemists, and production facilities in the pharmaceutical and biotechnology sectors seeking reliable, high-purity intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel penicillin and cephalosporin derivatives.
• Antibiotic Research & Development: Used in medicinal chemistry for the design and synthesis of new antibacterial agents with modified side chains.
• Process Chemistry: Serves as a critical building block in the scale-up and optimization of API (Active Pharmaceutical Ingredient) manufacturing processes.
• Chemical Biology: Utilized in the study of β-lactamase enzymes and the development of enzyme inhibitors.
• Fine Chemical Synthesis: Employed in the preparation of complex, bromine-containing organic molecules for various research applications.
• Reference Standard: Can be used as a high-purity analytical standard for quality control in pharmaceutical production.

Basic Information

Product Name	p-Nitrobenzyl-6,6-Dibromopenicillinate
CAS No.	98510-71-5
Molecular Formula	C₁₅H₁₄Br₂N₂O₅S
Molecular Weight	494.16 g/mol
Synonyms	6,6-Dibromopenicillanic Acid p-Nitrobenzyl Ester; p-Nitrobenzyl 6β-Bromo-6α-bromopenicillanate; PNBP-DB; 4-Nitrobenzyl 6,6-dibromopenicillinate; (2S,5R,6R)-6,6-Dibromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid 4-Nitrobenzyl Ester; 6α,6β-Dibromopenicillanic Acid p-Nitrobenzyl Ester; Dibromopenicillinate p-Nitrobenzyl Ester
EINECS	Contact for details

Quality Control

Our p-Nitrobenzyl-6,6-Dibromopenicillinate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines for the production of advanced intermediates, ensuring traceability and documentation for regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.