Description

trans-4-(Phenylmethoxy)Cyclohexanamine is a chiral amine derivative featuring a cyclohexylamine core substituted with a phenylmethoxy group. This compound is a valuable pharmaceutical intermediate and building block in organic synthesis, prized for its defined stereochemistry and functional handles for further chemical elaboration. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and other complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Ligand and Catalyst Precursor: Used in the preparation of chiral ligands for asymmetric catalysis and metal complexes.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides with specific stereochemical requirements.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, or advanced organic materials.
• Academic & R&D: A versatile reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	trans-4-(Phenylmethoxy)Cyclohexanamine
CAS No.	98454-39-8
Molecular Formula	C13H19NO
Molecular Weight	205.30 g/mol
Synonyms	trans-4-(Benzyloxy)cyclohexanamine; 4-(Phenylmethoxy)cyclohexanamine (trans-); trans-4-Benzyloxycyclohexylamine; 4-(Benzyloxy)cyclohexanamine; Cyclohexanamine, 4-(phenylmethoxy)-, trans-; 4-(Benzyloxy)cyclohexan-1-amine; 98454-39-8; Benzyl trans-4-aminocyclohexyl ether
EINECS	Contact for details

Quality Control

Our trans-4-(Phenylmethoxy)Cyclohexanamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.