Description

3,4,5,10-Tetrahydro-1β-Methyl-9-Hydroxy-5,10-Dioxo-1H-Naphtho[2,3-C]Pyran-3α-Acetic Acid is a high-purity, complex organic compound with a fused naphthopyran structure, serving as a critical advanced intermediate in pharmaceutical synthesis. Its precise stereochemistry and functional groups make it invaluable for constructing sophisticated molecular architectures in drug discovery and development. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for producing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting specific biological pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce specific chiral centers and functional group arrays.
• API Manufacturing: Serves as a precursor in the scaled-up production of advanced active pharmaceutical ingredients under GMP conditions.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies due to its specific structural features.

Basic Information

Product Name	3,4,5,10-Tetrahydro-1β-Methyl-9-Hydroxy-5,10-Dioxo-1H-Naphtho[2,3-C]Pyran-3α-Acetic Acid
CAS No.	98392-26-8
Molecular Formula	C₁₇H₁₆O₆
Molecular Weight	316.31 g/mol
Synonyms	1H-Naphtho[2,3-c]pyran-3-acetic acid, 3,4,5,10-tetrahydro-9-hydroxy-1β-methyl-5,10-dioxo-; (3α)-3,4,5,10-Tetrahydro-9-hydroxy-1-methyl-5,10-dioxo-1H-naphtho[2,3-c]pyran-3-acetic acid; 98392-26-8; 1-Methyl-9-hydroxy-5,10-dioxo-1H-naphtho[2,3-c]pyran-3α-acetic acid; Tetrahydro methyl hydroxy dioxo naphthopyran acetic acid.
EINECS	Contact for details

Quality Control

Our 3,4,5,10-Tetrahydro-1β-Methyl-9-Hydroxy-5,10-Dioxo-1H-Naphtho[2,3-C]Pyran-3α-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.