Description

n-Boc-2-Piperidinecarboxylic Acid is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block and versatile intermediate in the development of complex, biologically active molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from drug discovery to process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and other therapeutic areas.
• Peptidomimetics & Constrained Peptide Synthesis: Used to introduce the constrained pipecolic acid scaffold into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand & Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of activity-based probes and molecular tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring high-fidelity chiral induction.

Basic Information

Product Name	n-Boc-2-Piperidinecarboxylic Acid
CAS No.	98303-20-9
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	1-Boc-pipecolic acid; 1-(tert-Butoxycarbonyl)pipecolic acid; (R,S)-1-Boc-pipecolic acid; 1-Boc-2-piperidinecarboxylic acid; tert-Butyl pipecolate-1-carboxylate; 1-N-Boc-pipecolinic acid; Pipecolic acid, N-Boc-; 2-Piperidinecarboxylic acid, 1-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our n-Boc-2-Piperidinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.