Description

(3As)-6Aβ-Chloro-3Aβ,4,5,6,6A,7,7Aβ,8A,8Bβ,8Cα-Decahydro-6β,7α-Dihydroxy-6,8Aβ-Dimethyl-3-Methyleneoxireno[2,3]Azuleno[4,5-B]Furan-2(3H)-One is a complex, highly functionalized sesquiterpene lactone derivative, valued for its intricate stereochemistry and reactive functional groups. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile scaffold in synthetic organic chemistry for constructing novel molecular architectures. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and anti-inflammatory drug discovery.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel, biologically active sesquiterpene-based compounds.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis: Serves as a sophisticated starting material or chiral template for total synthesis projects and the development of new synthetic methodologies.
• Biochemical Research: Potential use as a probe or inhibitor in studying biological pathways involving specific enzyme or receptor targets.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(3As)-6Aβ-Chloro-3Aβ,4,5,6,6A,7,7Aβ,8A,8Bβ,8Cα-Decahydro-6β,7α-Dihydroxy-6,8Aβ-Dimethyl-3-Methyleneoxireno[2,3]Azuleno[4,5-B]Furan-2(3H)-One
CAS No.	98259-96-2
Molecular Formula	C17H21ClO5
Molecular Weight	340.80 g/mol
Synonyms	6Aβ-Chloro-3Aβ,4,5,6,6A,7,7Aβ,8A,8Bβ,8Cα-Decahydro-6β,7α-dihydroxy-6,8Aβ-dimethyl-3-methylideneoxireno[2,3]azuleno[4,5-b]furan-2(3H)-one; Chlorinated Sesquiterpene Lactone Derivative; Oxirenoazulenofuranone Derivative; CAS 98259-96-2
EINECS	Contact for details

Quality Control

Our (3As)-6Aβ-Chloro-3Aβ,4,5,6,6A,7,7Aβ,8A,8Bβ,8Cα-Decahydro-6β,7α-Dihydroxy-6,8Aβ-Dimethyl-3-Methyleneoxireno[2,3]Azuleno[4,5-B]Furan-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.