Description

Cyclopropanecarboxylic Acid, 1-Amino-2-Methyl-, Methyl Ester, Hydrochloride, cis- (9Ci) is a high-purity, stereochemically defined chemical building block of significant interest in advanced organic synthesis. Its core value lies in the unique strained cyclopropane ring and functionalized amino ester hydrochloride salt, which are critical for constructing complex molecular architectures with specific spatial orientations. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where precise stereochemistry is essential for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the creation of novel herbicides and insecticides, where the cyclopropane moiety can enhance stability and bioactivity.
• Chemical Biology & Proteomics: Serves as a specialized building block for synthesizing molecular probes and activity-based protein profiling (ABPP) reagents.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Material Science Precursor: Potential use in synthesizing specialty monomers for advanced polymers with unique mechanical properties.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Amino-2-Methyl-, Methyl Ester, Hydrochloride, cis- (9Ci)
CAS No.	98259-91-7
Molecular Formula	C7H14ClNO2
Molecular Weight	179.64 g/mol
Synonyms	cis-1-Amino-2-methylcyclopropanecarboxylic acid methyl ester hydrochloride; Methyl cis-1-amino-2-methylcyclopropanecarboxylate hydrochloride; (1R,2S)-1-Amino-2-methylcyclopropanecarboxylic acid methyl ester hydrochloride (and other stereoisomers); 1-Amino-2-methylcyclopropanecarboxylic acid methyl ester HCl; ACCA methyl ester hydrochloride; 2-Methyl-1-aminocyclopropanecarboxylic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-Amino-2-Methyl-, Methyl Ester, Hydrochloride, cis- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (cis-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.