Description

1-Hydroxyserirubicin is a key anthracycline derivative and a significant intermediate in the synthesis of advanced pharmaceutical compounds. This high-purity chemical is critical for research and development in oncology, enabling the creation of novel chemotherapeutic agents and targeted drug delivery systems. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing next-generation cancer treatments and conducting biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel anthracycline-based chemotherapeutic drugs.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of action, structure-activity relationships (SAR), and drug resistance in cancer cells.
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and method development for HPLC and LC-MS analysis of related compounds.
• Drug Discovery & Development: Integral to medicinal chemistry programs aimed at developing new anticancer agents with improved efficacy and reduced side-effect profiles.
• Bioconjugation Studies: Utilized in research exploring the attachment of active pharmaceutical ingredients (APIs) to antibodies, polymers, or other targeting moieties for targeted therapy.
• Metabolite Identification: Acts as a reference compound in the identification and quantification of drug metabolites during preclinical and clinical studies.

Basic Information

Product Name	1-Hydroxyserirubicin
CAS No.	98183-93-8
Molecular Formula	C26H29NO10
Molecular Weight	515.51 g/mol
Synonyms	1-Hydroxyserirubicin; 1-Hydroxy-serirubicin; 7-Deoxy-13-dihydrodaunorubicin 1-hydroxy derivative; 1-Hydroxy-7-deoxy-13-dihydrodaunorubicin; Serirubicin 1-hydroxy derivative; 1'-Hydroxyserirubicin; (1S,3S)-3-Glycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside
EINECS	Contact for details

Quality Control

Our 1-Hydroxyserirubicin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.