Description

1-(p-Fluoro-Phenyl-6-Fluoro-7-Chloro-4-Oxo-3-Quinolinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex fluorinated quinolinecarboxylic acid structure. This compound is critical for the synthesis of next-generation antibacterial agents, particularly fluoroquinolone antibiotics, due to its precise molecular architecture. It is an essential building block for pharmaceutical R&D and manufacturing teams focused on developing potent antimicrobial therapies.

Application

• Key Intermediate for Fluoroquinolone Antibiotics: Serves as a core precursor in the synthesis of advanced broad-spectrum antibacterial agents.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and development of new antimicrobial compounds with improved efficacy.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the commercial-scale production of finished dosage forms for antibiotic treatments.
• Chemical Synthesis Reference Standard: Acts as a high-purity standard for analytical method development and quality control in pharmaceutical labs.
• Process Chemistry Optimization: Utilized in scaling up and optimizing synthetic routes for complex heterocyclic molecules.

Basic Information

Product Name	1-(p-Fluoro-Phenyl-6-Fluoro-7-Chloro-4-Oxo-3-Quinolinecarboxylic Acid
CAS No.	98105-79-4
Molecular Formula	C17H8ClF2NO3
Molecular Weight	347.70 g/mol
Synonyms	1-(4-Fluorophenyl)-6-fluoro-7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-(p-Fluorophenyl)-6-fluoro-7-chloro-4-oxo-1,4-dihydro-3-quinolinecarboxylic Acid; 6-Fluoro-7-chloro-1-(4-fluorophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-(4-Fluorophenyl)-6-fluoro-7-chloro-4-oxoquinoline-3-carboxylic Acid; 7-Chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1,4-Dihydro-1-(4-fluorophenyl)-6-fluoro-7-chloro-4-oxo-3-quinolinecarboxylic acid; 4-Oxo-1-(4-fluorophenyl)-6-fluoro-7-chloro-1,4-dihydroquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(p-Fluoro-Phenyl-6-Fluoro-7-Chloro-4-Oxo-3-Quinolinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) documenting full specifications are available for every shipment to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.