Description

4-Fluoroandrostenedione is a fluorinated derivative of the natural steroid hormone androstenedione, serving as a key synthetic intermediate in advanced pharmaceutical research and development. This compound is valued for its role in modulating enzymatic pathways, particularly as a potent and selective inhibitor of aromatase, which is crucial for the study of hormone-dependent conditions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including those targeting oncology and endocrinology.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced steroid-based drugs and investigational new chemical entities.
• Biochemical Research: Used as a reference standard and tool compound in studies of steroidogenesis, enzyme kinetics, and aromatase inhibition mechanisms.
• Oncology Research: Investigated for its potential role in developing therapies for hormone-sensitive cancers, such as breast and prostate cancer.
• Endocrinology Studies: Employed in preclinical research to understand and manipulate estrogen biosynthesis pathways.
• Metabolite Synthesis: Utilized in the preparation of fluorinated steroid metabolites for analytical and diagnostic purposes.
• Academic & Industrial R&D: Serves as a high-purity chemical for method development and discovery chemistry within contract research organizations (CROs) and university laboratories.

Basic Information

Item	Details
Product Name	4-Fluoroandrostenedione
CAS No.	98102-30-8
Molecular Formula	C19H25FO2
Molecular Weight	304.40 g/mol
Synonyms	4-Fluoroandrost-4-ene-3,17-dione; 4-Fluoro-4-androstene-3,17-dione; 4-FAD; 4-Fluoroandrostenediol; 4-Fluoro-δ4-androstenedione; 4-Fluoroandrost-4-en-3,17-dione; 4-Fluoro-17-ketoandrost-4-en-3-one
EINECS	Contact for details

Quality Control

Our 4-Fluoroandrostenedione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.