Description

1-Ethyl-6,8-Difluoro-1,4-Dihydro-7-(3-Methyl-1-Piperazinyl)-4-Oxoquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial and research importance. This compound is a key synthetic precursor in the production of modern fluoroquinolone antibiotics, valued for its precise molecular structure which is critical for developing potent antimicrobial agents. It is primarily required by pharmaceutical R&D laboratories, API (Active Pharmaceutical Ingredient) manufacturers, and fine chemical synthesis specialists focused on next-generation antibacterial therapies.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel fluoroquinolone antibiotic candidates.
• Antibacterial Drug Development: Used in research and development of new antibacterial agents targeting resistant pathogens.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key precursor in the multi-step manufacturing process of final drug substances.
• Chemical Research: Employed in academic and industrial research to study structure-activity relationships (SAR) in quinolone chemistry.
• Process Chemistry & Scale-Up: Utilized for optimizing synthetic routes and scaling production from laboratory to pilot and commercial scale.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	1-Ethyl-6,8-Difluoro-1,4-Dihydro-7-(3-Methyl-1-Piperazinyl)-4-Oxoquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	98079-83-5
Molecular Formula	C19H23F2N3O3
Molecular Weight	379.40 g/mol
Synonyms	Ethyl 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate; 1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid ethyl ester; 7-(3-Methyl-1-piperazinyl)-1-ethyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester; Gatifloxacin Ethyl Ester; Gatifloxacin Intermediate; AM-1155 Ethyl Ester; GTX Ethyl Ester
EINECS	Contact for details

Quality Control

Our 1-Ethyl-6,8-Difluoro-1,4-Dihydro-7-(3-Methyl-1-Piperazinyl)-4-Oxoquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent specifications required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability, consistency, and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.