Description

(R)-Lomefloxacin CAS NO 98079-55-1 is the single enantiomer of the broad-spectrum fluoroquinolone antibiotic lomefloxacin. This optically pure form is critical for advanced pharmaceutical research and development, particularly in studying stereospecific biological activity and pharmacokinetics. It is an essential chiral intermediate and reference standard for analytical laboratories, pharmaceutical manufacturers, and academic institutions focused on antimicrobial agents and chiral chemistry.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for analytical method development, validation, and quality control (QC/QA) of lomefloxacin-based drug products.
• Chiral Intermediate: Serves as a key building block in the synthesis of novel, enantiomerically pure fluoroquinolone derivatives for preclinical research.
• Mechanistic & Metabolic Studies: Employed in pharmacological research to investigate the stereoselective mode of action, metabolism, and toxicity profile of lomefloxacin enantiomers.
• Analytical Chemistry: Essential for calibrating chromatographic systems (e.g., Chiral HPLC) and developing assays to determine enantiomeric purity.
• Academic Research: Used in university and institutional labs for studies in medicinal chemistry, microbiology, and stereochemistry.

Basic Information

Product Name	(R)-Lomefloxacin
CAS No.	98079-55-1
Molecular Formula	C17H19F2N3O3
Molecular Weight	351.35 g/mol
Synonyms	(R)-Lomefloxacin; (R)-(-)-Lomefloxacin; (R)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; Dexalomefloxacin; (R)-Enantiomer of Lomefloxacin; (R)-FCB; (R)-NY-198
EINECS	Contact for details

Quality Control

Our (R)-Lomefloxacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) providing batch-specific results for identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Enantiomeric Excess)	≥99.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.