Description

1-Aminocyclobutanecarboxylic Acid Hydrochloride is a high-purity, pharmaceutically relevant building block. This compound is valued for its unique constrained cyclobutane ring structure, which is integral to developing novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and peptide synthesis for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs) and investigational new drugs.
• Peptide Synthesis: Used as a constrained, non-proteinogenic amino acid analog to modify peptide backbones, enhancing metabolic stability and bioavailability.
• Medicinal Chemistry Research: Serves as a versatile building block in structure-activity relationship (SAR) studies and library synthesis for screening.
• Bioconjugation: The amine functionality allows for conjugation to other molecules, useful in creating targeted probes or drug-linker systems.
• Chemical Biology: Employed in the synthesis of enzyme inhibitors or receptor ligands that exploit the rigid geometry of the cyclobutane ring.
• Agrochemical Research: Potential intermediate in the synthesis of novel compounds with pesticidal or herbicidal activity.

Basic Information

Product Name	1-Aminocyclobutanecarboxylic Acid Hydrochloride
CAS No.	98071-16-0
Molecular Formula	C5H10ClNO2
Molecular Weight	151.59 g/mol
Synonyms	1-Amino-cyclobutanecarboxylic acid hydrochloride; (1-Aminocyclobutyl)carboxylic acid hydrochloride; Cyclobutane-1-carboxylic acid, 1-amino-, hydrochloride; ACBC hydrochloride; 1-Aminocyclobutanecarboxylic acid HCl; 1-Amino-1-carboxycyclobutane hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Aminocyclobutanecarboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.