Description

(1S)-(+)-(1-Aminopropyl)Phosphonic Acid is a high-purity, chiral organophosphorus compound that serves as a critical building block in advanced synthesis. Its unique structure, featuring both an amino and a phosphonic acid group on a chiral carbon, makes it a valuable ligand and intermediate for creating stereoselective catalysts and biologically active molecules. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure components for process development and scale-up.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of novel drug candidates, particularly those targeting bone metabolism and enzyme inhibition.
• Catalyst Ligand: Used in asymmetric synthesis as a component of metal-complex catalysts for producing enantiomerically enriched compounds.
• Agrochemical Research: Building block for developing new herbicides and plant growth regulators with specific modes of action.
• Chelating Agent: Effective sequestrant for metal ions in analytical chemistry and industrial water treatment formulations.
• Biomimetic Chemistry: Used to create analogs of naturally occurring phosphonates for studying biological pathways and enzyme mechanisms.
• Material Science: Monomer or additive for modifying polymer surfaces and creating functionalized materials with specific adhesion or corrosion-resistant properties.

Basic Information

Product Name	(1S)-(+)-(1-Aminopropyl)Phosphonic Acid
CAS No.	98048-99-8
Molecular Formula	C₃H₁₀NO₃P
Molecular Weight	139.09 g/mol
Synonyms	(S)-(+)-1-Amino-1-phosphonopropane; (1S)-1-Aminopropylphosphonic Acid; L-1-Aminopropylphosphonic Acid; (+)-(S)-1-Amino-1-phosphonopropane; (S)-1-Amino-propylphosphonic acid; 1-Aminopropylphosphonic acid, (S)-; Phosphonic acid, P-[(1S)-1-aminopropyl]-
EINECS	Contact for details

Quality Control

Our (1S)-(+)-(1-Aminopropyl)Phosphonic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting standards for research and commercial use. A Certificate of Analysis (COA) detailing specific results for identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.