Description

1-(n-Carbobenzoxy-γ-Glutamyl)Perhydroindoline-2-Carboxylic Acid is a specialized, high-purity peptide derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the research and development of complex pharmaceutical actives, particularly in peptide-based drug discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry Research: Used in academic and industrial laboratories for the study and development of novel peptide structures and their biological activities.
• Solid-Phase Peptide Synthesis (SPPS): Employed as a protected glutamyl derivative for the controlled elongation of peptide chains on resin supports.
• Prodrug Development: Acts as a precursor for designing prodrugs where specific amino acid sequences are required for targeted drug delivery and activation.
• Bioconjugation: Utilized in the chemical modification of proteins or other biomolecules to attach functional groups or labels.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Detail
Product Name	1-(n-Carbobenzoxy-γ-Glutamyl)Perhydroindoline-2-Carboxylic Acid
CAS No.	97975-46-7
Molecular Formula	C24H32N2O7
Molecular Weight	460.52 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-L-γ-glutamyl-perhydroindoline-2-carboxylic acid; Z-γ-Glu(Perhydroindoline-2-COOH); Cbz-γ-Glu(Perhydroindoline-2-COOH); N-Carbobenzoxy-γ-glutamyloctahydroindole-2-carboxylic Acid; (2S)-1-[(2S)-5-[(Benzyloxy)carbonylamino]-2-[(2S)-1,2,3,4,4a,5,6,7b-octahydro-1H-indol-2-yl]-5-oxopentanoyl]pyrrolidine-2-carboxylic acid (IUPAC); Z-γ-Glu(Perhydroindoline-2-COOH); CBZ-γ-Glutamyl-Perhydroindoline-2-Carboxylic Acid; 1-(N-Cbz-γ-Glutamyl)Perhydroindoline-2-Carboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-(n-Carbobenzoxy-γ-Glutamyl)Perhydroindoline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.