Description

3',5'-Di-o-(p-Toluoyl)-5-(2-Hydroxyethyl)-2'-Deoxyuridine is a key nucleoside derivative and a crucial intermediate in the synthesis of complex antiviral and anticancer pharmaceuticals. This high-purity building block is essential for research and development in advanced nucleoside chemistry, enabling the creation of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel antiviral and anticancer nucleoside analogs.
• Medicinal Chemistry Research: Used as a specialized building block for structure-activity relationship (SAR) studies and lead compound optimization.
• Antiviral Drug Development: Serves as a key intermediate in the production chain for experimental antiviral medications.
• Biochemical Research: Employed in studies involving DNA/RNA synthesis inhibition and enzyme-substrate interactions.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing of high-value, complex organic molecules.
• Academic & Institutional R&D: A valuable reagent for universities and research institutes exploring nucleoside chemistry and prodrug development.

Basic Information

Product Name	3',5'-Di-o-(p-Toluoyl)-5-(2-Hydroxyethyl)-2'-Deoxyuridine
CAS No.	97974-93-1
Molecular Formula	C28H28N2O8
Molecular Weight	520.53 g/mol
Synonyms	5-(2-Hydroxyethyl)-2'-deoxyuridine 3',5'-bis(4-methylbenzoate); 3',5'-Di-O-(4-methylbenzoyl)-5-(2-hydroxyethyl)-2'-deoxyuridine; 5-(2-Hydroxyethyl)-3',5'-di-O-p-toluoyl-2'-deoxyuridine; 2'-Deoxy-5-(2-hydroxyethyl)uridine 3',5'-bis(4-methylbenzoate); 97974-93-1; p-Toluoyl-protected 5-(2-Hydroxyethyl)-2'-deoxyuridine; Nucleoside intermediate 97974-93-1
EINECS	Contact for details

Quality Control

Our 3',5'-Di-o-(p-Toluoyl)-5-(2-Hydroxyethyl)-2'-Deoxyuridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) documenting purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.