Description

5,6-Diamino-2,2-Difluorobenzodioxole, Dihydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzodioxole core and difluoro substitution. This compound is of significant commercial importance for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds and novel drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its fluorinated benzodioxole structure for enhanced bioactivity and stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle or linker in the design of chemical probes and affinity tags for studying biological systems.
• Organic Synthesis Building Block: Provides a versatile scaffold for constructing complex molecular architectures in medicinal and process chemistry.

Basic Information

Product Name	5,6-Diamino-2,2-Difluorobenzodioxole, Dihydrochloride
CAS No.	97966-69-3
Molecular Formula	C8H8Cl2F2N2O2
Molecular Weight	281.07 g/mol
Synonyms	2,2-Difluoro-5,6-diaminobenzo[1,3]dioxole dihydrochloride; 2,2-Difluoro-1,3-benzodioxole-5,6-diamine dihydrochloride; 5,6-Diamino-2,2-difluoro-1,3-benzodioxole hydrochloride (1:2); 97966-69-3; 5,6-Diamino-2,2-difluorobenzodioxole HCl; 2,2-Difluoro-5,6-diaminobenzodioxole dihydrochloride
EINECS	Contact for details

Quality Control

Our 5,6-Diamino-2,2-Difluorobenzodioxole, Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.