Description

5-Trifluoromethoxy-1,3-Dihydro-2H-Benzimidazol-2-Thione is a high-value heterocyclic organic compound featuring a benzimidazole core functionalized with a trifluoromethoxy group and a thione moiety. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the development of specialty chemicals, ligands for catalysis, and advanced organic electronic materials.
• Chemical Biology Probes: Employed in academic and industrial research to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	5-Trifluoromethoxy-1,3-Dihydro-2H-Benzimidazol-2-Thione
CAS No.	97963-59-2
Molecular Formula	C8H5F3N2OS
Molecular Weight	234.20 g/mol
Synonyms	5-(Trifluoromethoxy)-1H-benzimidazole-2(3H)-thione; 5-(Trifluoromethoxy)-2-mercaptobenzimidazole; 2-Mercapto-5-trifluoromethoxybenzimidazole; 5-Trifluoromethoxy-2-benzimidazolethiol; 97963-59-2; 5-Trifluoromethoxy-2-mercaptobenzimidazole; Benzimidazole-2-thione, 5-(trifluoromethoxy)-1,3-dihydro-
EINECS	Contact for details

Quality Control

Our production of 5-Trifluoromethoxy-1,3-Dihydro-2H-Benzimidazol-2-Thione adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment. We support compliance with global regulatory frameworks, including REACH and cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.