Description

1-[3-(4-tert-Butylbenzoyl)Propyl]-4-Hydroxypiperidine is a specialized piperidine derivative featuring a 4-tert-butylbenzoyl functional group, serving as a crucial advanced pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals, where its specific molecular architecture enables targeted pharmacological activity. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and life science sectors for developing new therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production pathway for specific APIs requiring the 4-hydroxypiperidine moiety.
• Agrochemical Research: Serves as a precursor in the development of new generation pesticides and herbicides.
• Chemical Synthesis: Employed in organic synthesis for constructing complex molecules in academic and industrial R&D settings.
• Ligand and Catalyst Development: Potential use in creating chiral ligands or organocatalysts for asymmetric synthesis.
• Life Science Reagent: Utilized as a biochemical tool compound in pharmacological studies and target validation.

Basic Information

Product Name	1-[3-(4-tert-Butylbenzoyl)Propyl]-4-Hydroxypiperidine
CAS No.	97928-18-2
Molecular Formula	C19H29NO2
Molecular Weight	303.44 g/mol
Synonyms	4-Hydroxy-1-[3-(4-tert-butylbenzoyl)propyl]piperidine; 1-[3-(4-tert-Butylbenzoyl)propyl]-4-piperidinol; 4-(3-(4-(tert-Butyl)benzoyl)propyl)-1-piperidinol; 97928-18-2; 4-Hydroxy-1-(3-(4-tert-butylbenzoyl)propyl)piperidine; tert-Butyl 4'-(3-(4-hydroxypiperidin-1-yl)propyl)benzophenone derivative (related structure)
EINECS	Contact for details

Quality Control

Our 1-[3-(4-tert-Butylbenzoyl)Propyl]-4-Hydroxypiperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via IR and NMR, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) documenting all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.