Description

(2R)-2-Amino-2-[(3-Hydroxyphenyl)Methyl]Penta-3,4-Dienoic Acid is a specialized, non-proteinogenic amino acid derivative featuring a unique allene moiety and a chiral center. This compound matters as a sophisticated chiral building block and a key intermediate in the synthesis of complex bioactive molecules, offering precise structural control for advanced research and development. It is primarily needed by pharmaceutical R&D teams, medicinal chemists, and fine chemical manufacturers focused on creating novel drug candidates, enzyme inhibitors, and advanced peptidomimetics.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic disorders.
• Medicinal Chemistry Research: Used as a constrained scaffold or building block for designing and synthesizing novel peptidomimetics and enzyme inhibitors.
• Biochemical Probe Development: Employed in the creation of specialized probes and substrates to study enzyme mechanisms and receptor-ligand interactions.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective synthesis to introduce complex molecular architectures.
• Fine Chemical Production: Acts as a key intermediate in the multi-step synthesis of high-value, complex organic molecules for research and pre-clinical studies.

Basic Information

Product Name	(2R)-2-Amino-2-[(3-Hydroxyphenyl)Methyl]Penta-3,4-Dienoic Acid
CAS No.	97906-59-7
Molecular Formula	C₁₃H₁₅NO₃
Molecular Weight	233.26 g/mol
Synonyms	(2R)-2-Amino-2-(3-hydroxybenzyl)penta-3,4-dienoic acid; D-2-Amino-2-(3-hydroxybenzyl)-3,4-pentadienoic acid; (R)-2-Amino-2-((3-hydroxyphenyl)methyl)penta-3,4-dienoic acid; 2-Amino-2-(3-hydroxybenzyl)-3,4-pentadienoic acid (R-enantiomer); Allenic amino acid derivative; 97906-59-7; (R)-Hpda
EINECS	Contact for details

Quality Control

Our (2R)-2-Amino-2-[(3-Hydroxyphenyl)Methyl]Penta-3,4-Dienoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), chiral excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.