Description

Tamoxifen Acid is a key pharmaceutical intermediate and the primary active metabolite of the widely used breast cancer therapeutic, Tamoxifen Citrate. This compound is critical for the synthesis and research of selective estrogen receptor modulators (SERMs) due to its direct biological activity. It is essential for pharmaceutical manufacturers, research institutions, and laboratories focused on oncology drug development, hormone therapy research, and advanced metabolite studies.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of Tamoxifen Citrate and other related SERM therapeutics.
• Reference Standard: Serves as a high-purity chemical standard for analytical method development and quality control in drug manufacturing.
• Metabolite Research: Used in pharmacokinetic and pharmacodynamic studies to understand the metabolism and efficacy of Tamoxifen therapy.
• Biochemical Research: Employed in laboratory studies investigating estrogen receptor binding mechanisms and cellular signaling pathways.
• Active Pharmaceutical Ingredient (API) Development: A critical starting material for formulating novel drug delivery systems and prodrugs.

Basic Information

Product Name	Tamoxifen Acid
CAS No.	97818-93-4
Molecular Formula	C26H29NO
Molecular Weight	371.52 g/mol
Synonyms	Tamoxifen Acid; (Z)-Tamoxifen; (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine; trans-Tamoxifen; Metabolite E; Afimoxifene; ICI 47699; Z-Tamoxifen
EINECS	Contact for details

Quality Control

Our Tamoxifen Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical research and development. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.