Description

(Z)-1-[4-(2-Chloroethoxy)Phenyl]-1,2-Diphenyl-1-Butene is a high-purity, non-steroidal selective estrogen receptor modulator (SERM) intermediate. This compound matters for its critical role in the synthesis of advanced pharmaceutical agents, particularly in oncology and hormone therapy research. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions developing next-generation therapeutic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of selective estrogen receptor modulators (SERMs) and related therapeutic agents.
• Oncology Research: Used in the development and study of compounds targeting hormone-responsive cancers, such as breast cancer.
• Chemical Synthesis: Serves as a versatile precursor in organic synthesis for creating complex molecules with specific stereochemistry.
• Academic & Industrial R&D: Employed in research settings to investigate structure-activity relationships (SAR) and develop new chemical entities.
• Reference Standard: Can be utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	(Z)-1-[4-(2-Chloroethoxy)Phenyl]-1,2-Diphenyl-1-Butene
CAS No.	97818-83-2
Molecular Formula	C24H23ClO
Molecular Weight	362.89 g/mol
Synonyms	Zuclomiphene Impurity; (Z)-Clomiphene Impurity; (Z)-Clomiphene Related Compound; (Z)-1-(p-(2-Chloroethoxy)phenyl)-1,2-diphenyl-1-butene; (Z)-Enclomiphene Impurity; (Z)-Isomer of Clomiphene Impurity; (Z)-1-[4-(2-Chloroethoxy)phenyl]-1,2-diphenylbut-1-ene; Trans-Clomiphene Impurity
EINECS	Contact for details

Quality Control

Our (Z)-1-[4-(2-Chloroethoxy)Phenyl]-1,2-Diphenyl-1-Butene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available for every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	< 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.