Description

(S)-2-(4-Fluorophenylsulfonamido)-3-Phenylpropanoic Acid CAS NO 97801-53-1 is a high-purity chiral sulfonamide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, which are essential for constructing molecules with specific biological activity. This compound is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular targeting.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, especially protease inhibitors and enzyme-targeted therapies.
• Biochemical Research: Used as a reference standard or a precursor in studying enzyme-substrate interactions and structure-activity relationships (SAR).
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to introduce chiral centers into complex molecules.
• Peptidomimetics Development: Acts as a non-natural amino acid analog for creating peptide-like compounds with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for labeling and investigating biological pathways.

Basic Information

Product Name	(S)-2-(4-Fluorophenylsulfonamido)-3-Phenylpropanoic Acid
CAS No.	97801-53-1
Molecular Formula	C15H14FNO4S
Molecular Weight	323.34 g/mol
Synonyms	(S)-2-[(4-Fluorophenyl)sulfonyl]amino-3-phenylpropanoic acid; (S)-N-(4-Fluorobenzenesulfonyl)-phenylalanine; (S)-2-[(4-Fluorophenyl)sulfonamido]-3-phenylpropionic acid; L-N-(4-Fluorophenylsulfonyl)phenylalanine; (S)-Phe(4-F-SO2)-OH; 97801-53-1; (S)-2-(4-Fluorobenzenesulfonamido)-3-phenylpropanoic acid
EINECS	Contact for details

Quality Control

Our (S)-2-(4-Fluorophenylsulfonamido)-3-Phenylpropanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting R&D and cGMP standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.